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351

ganglioglioma and extra-cerebellar pilocytic astrocytoma.

Acta Neuropathol 121:397-405, 2011.

52. Kieran MW: Targeting BRAF in pediatric brain tumors. Am Soc

Clin Oncol Educ Book:e436-40, 2014.

53. Lawson AR, Tatevossian RG, Phipps KP, et al: RAF gene fusions

are specific to pilocytic astrocytoma in a broad paediatric

brain tumour cohort. Acta Neuropathol 120:271-3, 2010.

54. Jacob K, Albrecht S, Sollier C, et al: Duplication of 7q34 is

specific to juvenile pilocytic astrocytomas and a hallmark of

cerebellar and optic pathway tumours. Br J Cancer 101:722-

33, 2009.

55. Horbinski C: To BRAF or not to BRAF: is that even a question

anymore? J Neuropathol Exp Neurol 72:2-7, 2013.

56. Dahiya S, Emnett RJ, Haydon DH, et al: BRAF-V600E mutation

in pediatric and adult glioblastoma. Neuro Oncol 16:318-9,

2014.

57. Zhang J, Wu G, Miller CP, et al: Whole-genome sequencing

identifies genetic alterations in pediatric low-grade gliomas.

Nat Genet 45:602-12, 2013.

58. Penman CL, Faulkner C, Lowis SP, et al: Current Understanding

of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic

Targeting in Pediatric Low-Grade Gliomas. Front Oncol 5:54,

2015.

59. Schwartzentruber J, Korshunov A, Liu XY, et al: Driver

mutations in histone H3.3 and chromatin remodelling genes

in paediatric glioblastoma. Nature 482:226-31, 2012.

60. Wu G, Broniscer A, McEachron TA, et al: Somatic histone H3

alterations in pediatric diffuse intrinsic pontine gliomas and

non-brainstem glioblastomas. Nat Genet 44:251-3, 2012.

61. Khuong-Quang DA, Buczkowicz P, Rakopoulos P, et al: K27M

mutation in histone H3.3 defines clinically and biologically

distinct subgroups of pediatric diffuse intrinsic pontine

gliomas. Acta Neuropathol 124:439-47, 2012.

62. Castel D, Philippe C, Calmon R, et al: Histone H3F3A and

HIST1H3B K27M mutations define two subgroups of diffuse

intrinsic pontine gliomas with different prognosis and

phenotypes. Acta Neuropathol 130:815-27, 2015.

63. Venneti S, Santi M, Felicella MM, et al: A sensitive and specific

histopathologic prognostic marker for H3F3A K27M mutant

pediatric glioblastomas. Acta Neuropathol 128:743-53,

2014.

64. Solomon DA, Wood MD, Tihan T, et al: Diffuse Midline

Gliomas with Histone H3-K27M Mutation: A Series of 47

Cases Assessing the Spectrum of Morphologic Variation and

Associated Genetic Alterations. Brain Pathol 26:569-80,

2016.

65. Ryall S, Buczkowicz P, Arnoldo A, et al: Abstract B12: H3-K27M

is a negative prognostic marker in high- and low-grade

pediatric thalamic glioma. Cancer Research 76:B12-B12,

2016.

66. Seton-Rogers S: Glioma: Targeting a histone mutant. Nat Rev

Cancer 15:2-2, 2015.

67. Stupp R, Mason WP, van den Bent MJ, et al: Radiotherapy plus

concomitant and adjuvant temozolomide for glioblastoma. N

Engl J Med 352:987-96, 2005.

68. Van den Bent M, Vogelbaum M, Erridge S, et al: ACTR-04.

results of the interim analysis of the eortc randomized phase

iii catnon trial on concurrent and adjuvant temozolomide in

anaplastic glioma without 1p/19q co-deletion, an intergroup

trial. Neuro-Oncology 18:vi1-vi2, 2016.

69. Wick W, Weller M, van den Bent M, et al: MGMT testing--the

challenges for biomarker-based glioma treatment. Nat Rev

Neurol 10:372-85, 2014.

70. Kleinschmidt-DeMasters BK, Aisner DL, Birks DK, et al:

Epithelioid GBMs show a high percentage of BRAF V600E

mutation. Am J Surg Pathol 37:685-98, 2013.

71. New P: An Unusual Case of Resistant Secondary Glioblastoma

with BRAF V600e Mutation (P3.279). Neurology 86, 2016.

72. Robinson GW, Orr BA, Gajjar A: Complete clinical regression

of a BRAF V600E-mutant pediatric glioblastoma multiforme

after BRAF inhibitor therapy. BMC Cancer 14:258, 2014.

73. Bautista F, Paci A, Minard-Colin V, et al: Vemurafenib in

pediatric patients with BRAFV600E mutated high-grade

gliomas, Pediatr Blood Cancer, 2013.

74. Hyman DM, Puzanov I, Subbiah V, et al: Vemurafenib in

Multiple Nonmelanoma Cancers with BRAF V600 Mutations.

New England Journal of Medicine 373:726-736, 2015.

75. Long GV, Stroyakovskiy D, Gogas H, et al: Combined BRAF and

MEK Inhibition versus BRAF Inhibition Alone in Melanoma.

New England Journal of Medicine 371:1877-1888, 2014.

76. Berghoff AS, Kiesel B, Widhalm G, et al: O6.02analysis of

pd1 and pd-l1 expression in glioblastoma. Neuro-Oncology

16:ii12-ii12, 2014.

77. Nduom EK, Wei J, Yaghi NK, et al: PD-L1 expression and

prognostic impact in glioblastoma. Neuro-Oncology 18:195-

205, 2016.

[CLINICAL RELEVANCE OF MOLECULAR MARKERS IN GLIOMAS - Varun Monga, MBBS, et al]