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PSICOFÁRMACOS
TIPOS DE PATOLOGÍA MÉDICA
Hepática
Cardíaca
Renal
Antidepresivos
ISRS (paroxetina, sertralina,
escitalopram)
ISRSN (desvenlafaxina)
ISRS (escitalopram, sertralina) ISRS
Antipsicóticos
Haloperidol, sulpiride,
amisulpride
Haloperidol
Haloperidol, olanzapina
Estabilizadores del ánimo
Litio
Valproato, carbamazepina,
lamotrigina
V
alproato, carbamazepina,
lamotrigina
Ansiolíticos e hipnóticos
Lorazepam
Benzodiacepinas, zolpidem,
buspirona
Lorazepam, zopiclona
TABLA 1.
Psicofármacos con menor perfil de riesgo según patología médica
1.
Ruiz A. Psicofarmacología en condiciones médicas especiales. En Silva H
(editor). Manual de Psicofarmacología Clínica, 2ª Edición. Santiago de
Chile, Editorial Mediterráneo, 2016.Págs. 181-188.
2.
Owen J, Crouse E. Pharmacokinetics, Pharmacodinamics, and principles
of Drug-Drug Interactions. EnLevenson JL, Ferrando SJ (editores). Clinical
Manual of Psychopharmacology in the medically ill. Second Edition.
Arlington, American PsychiatricAssociation Publishing, 2017. Págs.
3-44.
3.
Telles-Correia D, Guerreiro DF, Coentre R, Zuzarte P, Figueira L.
Psychopharmacology in medical illness: cardiology, nephrology,
hepatology. Acta Med Port. 2009 Nov-Dec;22(6):797-808.
4.
Taylor D, Paton C,Kapur S. The Maudsley Prescribing Guidelines in
Psychiatry, 12th Edition. Chichester, Wiley-Blackwell, 2015.
5.
Trzepacz PT, Brenner R, Van Thiel DH. A psychiatric study of 247 liver
transplantation candidates. Psychosomatics. 1989 Spring;30(2):147-
53.
6.
Hale AS. Newantidepressants: use in high-risk patients. J Clin Psychiatry.
1993 Aug;54 Suppl:61-70.
7.
CroneC,MarcangeloM,LackampJ,DiMartiniA,OwenJA.Gastrointestinal
Disorders. En Levenson JL, Ferrando SJ (editores). Clinical Manual of
Psychopharmacology in the medically ill. Second Edition. Arlington,
American PsychiatricAssociation Publishing, 2017. Págs. 129-193.
8.
Thyrum PT, Wong YW, Yeh C. Single-dose pharmacokinetics
of quetiapine in subjects with renal or hepatic impairment.
ProgNeuropsychopharmacolBiol Psychiatry. 2000 May;24(4):521-33.
9.
Caparros-Lefebvre D, Lecomte-HouckeM, Pruvot FR, Declerck N, Paris JC,
Petit H. Unusual electronmicroscopic changes in valproate-associated
liver failure. Lancet. 1993 Jun 19;341(8860):1604.
10. Poto
č
njak I, Degoricija V, Vuki
č
evi
ć
Baudoin D,
Č
ulig J, Jakovljevi
ć
M.
Cardiovascular side effects of psychopharmacologic therapy. Int J
Cardiol. 2016 Sep 15;219:367-72.
11. Shapiro PA. Cardiovascular disorders. En Levenson JL, Ferrando SJ
(editores). Clinical Manual of Psychopharmacology in the medically ill.
Second Edition. Arlington, American PsychiatricAssociation Publishing,
2017. Págs. 233-270.
12. Jiang W, Davidson JR. Antidepressant therapy in patients with ischemic
heart disease. AmHeart J. 2005 Nov;150(5):871-81
13. Wang JT, Hoffman B, Blumenthal JA. Management of depression
in patients with coronary heart disease: association, mechanisms,
and treatment implications for depressed cardiac patients. Expert
OpinPharmacother. 2011 Jan;12(1):85-98
14, Stöllberger C1, Huber JO, Finsterer J. Antipsychotic drugs and QT
prolongation. IntClinPsychopharmacol. 2005 Sep;20(5):243-51.
15. HasnainM, ViewegWV. QTc interval prolongation and torsade de pointes
associated with second-generation antipsychotics and antidepressants:
a comprehensive review. CNS Drugs. 2014 Oct;28(10):887-920.
16. Fukunishi I, Sugawara Y, Takayama T, Makuuchi M, Kawarasaki
H, Surman OS. Association between pretransplant psychological
assessments and posttransplant psychiatric disorders in living-related
transplantation. Psychosomatics. 2002 Jan-Feb;43(1):49-54.
17. Friedli K, Almond M, Day C, Chilcot J, GaneMda S, Davenport A et al. A
study of sertraline in dialysis (ASSertID): a protocol for a pilot randomised
controlled trial of drug treatment for depression in patients undergoing
haemodialysis. BMC Nephrol. 2015 Oct 26;16:172.
18. Jain N, Trivedi MH, Rush AJ, Carmody T, Kurian B, Toto RD, et al. Rationale
and design of the Chronic Kidney Disease Antidepressant Sertraline Trial
(CAST). ContempClin Trials. 2013 Jan;34(1):136-44.
19. Levenson J, Owen J. Renal and urological disorders. En Levenson JL,
Ferrando SJ (editores). Clinical Manual of Psychopharmacology in the
medically ill. Second Edition. Arlington, American PsychiatricAssociation
Publishing, 2017. Págs. 195-231.
20. Jacobson S. Psychopharmacology: prescribing for patients with hepatic
or renal dysfunction. Psychiatr Times 2002; 19:65-70.
El autor declara no tener conflictos de interés, en relación a este artículo.
REFERENCIAS BIBLIOGRÁFICAS
[REV. MED. CLIN. CONDES - 2017; 28(6) 830-834]
ISRS: Inhibidores selectivos de la recaptura de serotonina.